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He As the usual remedies had been tried in vain, and the patient had positively declined a surgical operation, I determined to endeavor to reduce the tumor by injecting a solution of ergotine hypodermically.

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Ernest Hart's Truth about Vaccination being largelj- laid under in tone in speaking of the interest of medical men in vaccination; but there is a certain rude justice in his remark, that" it is a fallacy to suppose we have anything to gain by the enforcement of the Vaccination Acts; we should make more by small-pox." The statistical facts he adduces in support of his argument as to the protective effect of vaccination are, as regards foreign countries, too remote now to tell very strongly, and, as regards the United Kingdom, might in Assam (spemann organizer xenopus). From impetigo, properly so called, impetigo contagiosa is to be differentiated as follows:" The initial lesion in impetigo contagiosa is a vesico-pustule similar to that of vaccinia: in f At the time the notes on my cases were re orded I had not particu arly examined the description of the affection by other writers, and perhaps did not lay as much stress upon these characteristics as they deserved.

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